Alzheimer's disease is named after Dr. Alois Alzheimer, a German physician. After its first discovery in 1906, Alzheimer's disease has always been an issue that the world attention focused on. According to the Alzheimer's Society, Alzheimer's disease is a chronic neurodegenerative disease that gradually gets worse over time and is the most common cause of dementia. Currently, there are nearly 44 million people suffering from Alzheimer's disease. Although there has been vast amount of research on Alzheimer's disease, the perfect medicine for it is not yet developed. However, KIST research team has delivered the news that it developed a new medicine that could completely cure the Alzheimer's disease. It is called EPPS.
The principle of EPPS
The medicine perfectly removes the β-Amyloid from the brain, so the dementia symptoms recovers to the normal level. β-Amyloid is the fundamental protein that causes Alzheimer's disease. β-Amyloid is commonly distributed in brains of normal people, but in case of Alzheimer, it is found in aggregate morphology in the brain. This medicine releases these clumps of β-Amyloid into nontoxic monomers. In fact, it also prevents acute secretion of GABA, which provokes the brain function to decline substantially. The dosing procedure is incredibly simple; the medicine is dosed with water like any ordinary medicine as it is easily integrated into the brain. |
| Morris water maze |
EPPS was injected into a mouse suffering from the Alzheimer's disease and its brain was examined for over 3 months. All the clumps of β-Amyloid, which were present on Hippocampus and Celebral cortex before the injection were successively removed. (Hippocampus and Celebral cortex take in charge of the recognition ability in the brain.) Then, the mouse's memory was tested by several tests such as Y-maze, Fear conditioning, and Morris water maze. The results showed that the mouse's recognition ability recovered to the normal level. After its successive demonstration, KIST is currently waiting for EPPS's clinical demonstration before its appearance in the pharmacy. I hope that the EPPS substantially decreases the fatality rate of Alzheimer's disease.KSJ
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