Saturday, 24 October 2015

#48 Why do we laugh when we get tickled? (English)

Why do we laugh when we get tickled?


It is common knowledge to all that when you get tickled by someone, you may start to laugh. This seems strange as it is not possible to tickle yourself! To many, to get tickled is not pleasant so why do we feel the need to laugh?

There are actually two different types of tickling; gargalesis and knismesis.

Gargalesis is a type of tickle which produces laughter and knismesis only causes an itching sensation.

It has been shown that when we get touched by a tickling motion by another, our somatosensory cortex and the anterior cingulated cortex get affected and these two create what we know as the tickling sensation. We have millions of nerve endings under our skin and when these get stimulated by touch for example, the message gets sent to the brain and then processes it to know whether or not it is important. This is why it is not possible to tickle ourselves as the brain knowns the action is coming and this message therefore becomes an unnecessary piece of information and doesn't react. As for when a different person does the same thing to us we react differently as it is an exterior stimulation.

The reason why we laugh when getting tickled is actually thought to be because it shows "submission to the aggressor". With this said, it means that, as we know, our most vulnerable places to get tickled are the places which are the easiest to get hurt, like for example our necks and ribcage. This then shows that these places are sensible and we know that we show be careful to not hurt ourselves in these places.

In conclusion, when we get tickled, our brain tells us to laugh as it is a sort of defense mechanism and it also shows us where we are most sensitive. Tickling is therefore an involuntary response to the exterior environment.

Resources:
http://mentalfloss.com/article/57808/why-do-we-laugh-when-were-tickled
http://science.howstuffworks.com/life/inside-the-mind/emotions/laugh-tickling2.htm

PRM

#47 Les Alternatives aux antibiotiques (Français)

Les Alternatives aux antibiotiques 

Il existe des méthodes plus naturelles qui pourraient suppléer aux antibiotiques. Premièrement, le miel a déjà été souvent utilisé par les Anciens Égyptiens. Le médicament issu du miel porte le nom de Medihoney. Deuxièmement, les probiotiques sont prometteuses dans le domaine médical. Ce sont des bactéries bénéfiques qui contrarient la bactérie Clostridium. Malgré le manque d'expériences, ces méthodes seront plus importantes en médecine dans les années à venir.

En premier lieu, Medihoney peut traiter la plaie. L'activité antimicrobienne du miel provoque une osmose étant donné qu'elle possède une grande concentration de sucre. Par conséquent, des tissus environnants et des bactéries sortent le corps avec le liquide. La glucose oxydose qui est une enzyme produit par les abeilles dans le miel supprime les bactéries et les antimicrobiens sans effet secondaire. D'ailleurs, les composés phytochimiques dans le nectar empêchent l'action bactéricide du miel. Quand le miel est suffisamment stérilisé, avec un coût abordable, la plaie est soignée. Au contraire, le miel alimentaire ne peut pas être utilisé pour le traitement Medihoney. Dans les pires cas, l'abus du miel pourrait provoquer des maladies sérieuses.

En second lieu, les probiotiques sont des bactéries bénéfiques qui guérissent les bactéries toxiques comme la bactérie Clostridium. Ensuite, il existe plusieurs effets bénéfiques grâce aux probiotiques. Premièrement, le traitement avec les probiotiques réduit l'impact de l'eczéma atopique des nouveau-nés. Deuxièmement, il ressemble au système immunitaire qui résiste contre l'asthme, d'autres types d'allergies et les syndromes du système digestif. C'est-à-dire, les probiotiques sont des antibiotiques qui agissent sur les bactéries pathogènes. En revanche, les preuves pour assurer et sécuriser les probiotiques sont insuffisantes pour les réaliser à grande échelle.

En conclusion, l'avenir du domaine de la médicine est prometteur avec le développement des traitements qui pourront remplacer les antibiotiques. Bien qu'ils ne soient pas encore en état de réalisation, leurs vertus sont intéressantes.

Référence
Le Devoir par Pauline Gravel
Alternative Santé

KSJ

Friday, 23 October 2015

#46 The effect of music on concentration (English)


The Effect of Music on Concentration
Introduction
 
The aim of our experiment was to see whether no music, classical music or hard rock had a better effect on concentration. Our hypothesis was that the completion rate of the maze would be highest when the participants listened to jazz music. An alternate hypothesis would be that the completion rate would be higher when listening to heavy metal. The null hypothesis would be that the completion rate remained the same throughout all three conditions and therefore music had no effect on concentration.

This hypothesis was selected because we believed that the more distracting the music, the lower the concentration. This is an example of a directional hypothesis as we predicted that jazz music would increase concentration. A non-directional hypothesis simply states that there is an effect but does not explain in which direction. 
The independent variable in our experiment, the one we changed, was the type of music the participants listened to. The dependent variable, the one we measured and observed, was the maze completion rate in each condition. A confounding variable would be if the participants listened to their music at different levels, this was easily rectified by making sure each participant listened at equal volumes. Another confounding variable would be if the participants were already used to this genre of music and therefore did better. This could be rectified by carrying out a survey prior to the experiment.
As it is hard to fully define and measure what exactly concentration is, this experiment just focused on the ability to complete a maze in given circumstances. This is known as operationalizing.

Method

The maze used in the experiment
The experimental method involves the manipulation of one or more variables to determine their effect on a dependent variable. Strengths of using the experimental method involve the ability to replicate the experiment as it was carried out with a standardized procedure. This however leads to the lack of ecological validity as the artificiality of the setting may produce unnatural behavior that does not reflect real life. Experiments are conducted in a controlled environment enabling the researcher to eliminate as many extraneous variables as possible which leas to less confounding results. This allows a cause and effect relationship to be established. Other limitations include the existence of demand characteristics and experimenter effects. Participants may figure out what the aim of the experiment is and therefore alter their responses or behavior to ensure adequate results are provided and helpful. 
The design that we used was the independent measures design. By using this design each participant was only in one condition rather than all three. If we had used a repeated measures design the participants would either of had to complete the same maze or complete a different maze. Each circumstance leads to confounding variables. If the same maze was used for all three conditions, results would be contaminated by order effects where the participants have remembered the path and therefore do better the second and third time they do the maze. If a different maze was used in each condition, it would be hard to measure the difficulty and make a valid comparison.
The sampling style we used was random sampling however this turned out to be haphazard sampling as all the participants were from the same socio-economic background. This meant that our sample lacked representativeness. Stratified sampling would be more representative as it is a probability sampling technique where the researcher divides the entire population into different subgroups, then randomly selects the final subjects proportionally from the different strata.
Procedure
1.       Participants were asked to get out their iPad and earphones, those without earphones were provided with them as all already had iPads.
2.       A pen was provided for each participant if they did not have one.
3.       They were then randomly and equally split into three groups, however as there were only three boys, one was placed in each condition.
4.       Each group was assigned to a different table and spread out.
5.       Participants signed the informed consent form and received a full briefing.
6.       Participants were asked to search the required song on their iPads and make sure their volume was relatively high.
7.       The mazes were then distributed upside down and each participant was asked to write their group on the back of the paper.
8.       Participants were given 1 minute to complete the maze.
9.       After 1 minute the mazes were collected.

Ethics
In order to conduct a moral experiment ethics have to be taken into consideration. Informed consent is required before any research is carried out to make sure that the participant is ok with taking part. Participants must be fully debriefed about the actual aim of the experiment and offered the opportunity to withdraw their results after the experiment has been completed. Results must remain confidential once given consent. In our experiment the participants were not deceived in any way nor did they undergo any mental, physical or emotional harm and therefore we can conclude that an ethical experiment was carried out.
Results

There were four participants in each group. The completion rate was calculated by dividing the number completed by 4 and multiplying by 100 to receive a percentage.
Our results show that the overall completion rate was highest in the conditions where the participants listened to either jazz or just in silence. This proves our hypothesis. The completion rate in the rock group was 50% while the completion rate in the jazz group was 75%.
Discussion
This experiment could have been improved by using a larger sample size to increase reliability as four people is too small. Not only this but our sample was not very representative as we only used IB students so it is not easy to generalize. The background of the student was unknown as well which may of skewed results. We did not conduct any sort of survey before hand which meant that perhaps a student in the jazz group was already used to listening to this genre while studying and therefore could concentrate more.
Our results have shown us that music does indeed have an effect on concentration. Completing the maze listening to either jazz or in silence produced the same completion rate. We can therefore see that it may be lyrics which have an effect on concentration rather than the actual music itself as the jazz was instrumental. This however can not be proven with these results and only further research can back up this claim. In order to develop this topic further, more research such as surveys, interviews and observations may provide more evidence to show that different types of music have an effect on concentration levels. These results support the attention drainage effect which states that music with a higher intensity is more distracting and has a greater effect on task performance and concentration. This information could be used to improve student's learning at schools.

Certain flaws in our methodology include gender imbalance and outside noise. Although the ratio of boys to girls was the same in each condition, it was an unequal ratio of 1:3. As for the outside noise, this may have affected results as the participants in the control group with no music could hear the music of the other participants in separate conditions.
Appendix
Materials

        Song “Hard Rock Hallelujah” by Lordi
        Song "Best of Jazz instrumental jazz music for working-30 famous jazz standards"
        iPad
        Earphones
        A pen for each participant
        Standardized briefing instructions
        Standardized debriefing instructions
        Informed consent note
        Timer

Music links:
Hard rock hallelujah http://youtu.be/uGe8qID9gSs
30 minutes of jazz http://youtu.be/TZM0eOW7c6w

McA

#45 Crying (English)


Crying


What is crying?
Crying is the shedding of tears in response to an emotional state.

Why do we cry ?
Crying can be seen as a voluntary action but it is mostly seen as an involuntary action caused by emotions. American psychiatrists believe that crying has a lot of benefits as it is ways for patients and society to release their pain and their feelings. Crying does not only hold benefits for you but for the people around you. If you begin to cry , it is a sort of signal to the people surround you to inform them that you are frustrated or overwhelmed or in need for someones attention. In psychiatries, crying patients enable the psychiatrists to understand what the patient is feeling.Crying is not understood yet by scientists however they believe that it also has some form of biochemical purpose. It is believed to release stress hormones and toxins from the body. Lastly,crying is also useful when used as a social function for example, to get what you want by making the people around you feel bad for you.

Women cry more than men, is this true? Who cry the most?
Women tend to cry more than men do but experts believe that this is simply because men feel that crying will create an image of weakness. « When it comes to crying, the population as a whole is on a spectrum with some crying easily and others rarely ».

Scientists are not sure about what causes some people to cry more or easier. All we know is that it has something to do with temperament. However another reason is that some people are more emotional than other and provoke tears easier is because they have had a tough past. People with a a harsh history of trauma have been found to cry more and especially if they cannot seem to forget about their trauma. If a person refers back to their past it will generate more feelings of hurt leading to them generating more tears.

Reference
 
HIS

Sunday, 18 October 2015

#44 La greffe xénogénique (Français)

La greffe xénogénique


La greffe xénogénique est la transplantation des cellules vivantes  et des tissus prélevés chez l'animal pour remplacer les organes des humains. Comme 3'500 greffes sont accomplies chaque année en France, cette technique médicale est prometteuse. Bien qu'il y ait des effets secondaires, elle semble être une solution pour contrer un avenir incertain.

D'un côté, dans la situation actuelle où il y a une miniaturisation du commerce du corps humain mais une augmentation des patients, la greffe xénogénique est une solution. Quant à la stabilité, la similitude anatomique  de ces organes des animaux avec les hommes permet la concordance. Quoi qu'aux balbutiement, le succès de la greffe xénogénique permet le traitement du diabète ou des maladies neurodégénératives, telles que la maladie de Parkinson. Il persiste des inquiétudes sur le phénomène du rejet. Néanmoins, ce phénomène est un fait naturel qui survient également après la transplantation interhumaine. Selon une théorie, un organe d'origine animale est tout aussi compatible, donc la greffe xénogénique obtient plus de soutien.

D'un autre côté, il est impossible de nier l'effet secondaire qui est la transmission des maladies. En fait, plusieurs infections fâcheuses des hommes sont d'origine animale. Ce problème prend de l'ampleur dans des pays où une surveillance appropriée de cette opération est inexistante. Selon une expérience réelle par un américain qui avait reçu un foie de babouin, il souffrait d'une hépatite B après l'opération. Dans des cas extrêmes, le rejet provoque la destruction du système immunitaire. De plus, dans une perspective éthique, la greffe xénogénique peut angoisser psychologiquement le patient.

En conclusion, la transplantation de l'animal à l'homme, la greffe xénogénique, pourrait être le remède pour le manque d'organes pour les humains. En revanche, cette pratique est encore au début et elle a besoin de modifications pour réussir l'implantation.

Reference:
www.oms.org
L'Humanité (21/11/2006)

KSJ

Saturday, 17 October 2015

#43 Excretion in humans (English)

EXCRETION IN HUMANS
Excretion is the removal of toxic materials, the waste products of metabolism and substances in excess of requirements from organisms. Metabolism is chemical reactions taking place inside cells, including respiration.

The body excretes four main waste materials. There are carbon dioxide, urea, water and salts.

The Excretory system of humans is made up of 4 structures: Two kidneys, two ureters, a bladder, and the urethra. The kidneys act as a filter to filter the waste products from the blood, the ureters are tubes that transport the main waste products (urine) from the kidneys to the bladder, where it is stored until it is excreted out of the body through the urethra.

 Formation of Urea

(Urea is formed in the liver from excess amino acids)

1.       When you eat a food high in protein, it is digested in the small intestine into amino acids.
2.       The villi on the walls of the small intestine absorb the amino acids into the hepatic portal vein.
3.       The hepatic portal vein is a special vein that transports digested material from the small intestine to the liver.
4.       The liver plays a big role in maintaining the level of protein in our body. It absorbs all amino acids from the hepatic portal vein.
-         If the body needs proteins, they will pass through the liver into the blood stream to be used by the body cells to make protein.
-         If the body does not need proteins. The liver will absorb excess amino acids and break them down into carbohydrates and nitrogen. The formula of amino acids is CHON; here we remove the nitrogen from the molecule, to get a carbohydrate. This is called deamination. Nitrogen is made into urea, which is a nitrogenous waste product.
5.       The products are then released to the blood stream.

Kidneys Structure

- A kidney consists of two main structures:

    Cortex (outer layer)
    Medulla

- Between the cortex and the Medulla, there is a structure called the nephron.

The nephron is the where filtration of toxic materials from the blood takes place. We have many of them in each kidney.

- In the centre of the kidney there is a cavity called the pelvis, which leads to the ureter.

 Structure of Nephron

The nephron starts with a cup shaped structure called Bowman’s capsule. Inside the Bowman’s capsule there is a very dense network of blood capillaries entering as capillaries from the renal artery and exiting as capillaries from the renal vein. This dense network of capillaries is called the Glomerulus. The rest of the nephron is a long coiled tube where materials filtered from the blood flow called the tubule. At some point the tubule becomes straight and is bent in a U shape tube, this part is called loop of Henle and it is surrounded by a network of capillaries from the renal vein, it is where reabsorption takes place. All tubules end at a large tube called the collecting duct where the content of the nephrons are transported to the pelvis, to be secreted in the ureter.

 Mechanism of the Kidneys

Ultrafiltration

The blood in the renal artery contains large amounts of urea, glucose, water, mineral ions (salts) and some amino acids. When it reaches the glomerulus, the high pressure of the blood and the concentration gradient of these materials between the blood and the nephron cause most of these substances to diffuse from the blood to the bowman’s capsule and become content of the tubule, which is called glomerular filtrate (glomerular filtrate is a mixture of urea, water, glucose and mineral ions that diffused from the blood to the nephron).

Reabsorption

The glomerular filtrate moves in the tubule till it reaches the loop of Henle, which is surrounded by a dense network of blood capillaries of the renal vein. Here there is a concentration gradient of the content of the nephron between the tubule and the blood. Both diffusion and active transport occur to ensure the complete reabsorption of valuable substances from the glomerular filtrate back to the blood; these substances are glucose and amino acids. Some water also moves by osmosis to the blood, as well as some salts.

That leaves urea, excess water and minerals to continue in the tubule till it reaches the collecting duct and the pelvis. This mixture is called urine. Urine is transported from the pelvis to the urinary bladder by the ureters. It is then secreted out of the body through the urethra.

Treating kidney failure

Sometimes a person’s kidneys may stop working. If this happens, the kidneys can no longer remove urea or excess water from the blood, and so may begin to feel very ill.

-      The best method of treatment in a kidney transplant. A kidney is taken from a donor and placed in the recipient’s body. It must be a good match or else the recipient’s immune system will attack and destroy it (This is called transplant rejection). The recipient will need to take immunosuppressant drugs for the rest of his or her life to stop the immune system from rejecting the kidney.

-        The alternative to a transplant rejection is dialysis. This involves filtering the patient’s blood on a regular basis with a machine, in a similar way to the kidney. During the process a tube is attached from the patient’s vein to the dialysis machine. Blood is sucked from the patient’s vein, it goes through the machine, and out from the other side back to the patient’s vein.

When the blood enters the dialysis machine, it is very rich in waste materials (urea, excess water and minerals).  The tubes inside the dialysis machine are made of a partially permeable membrane to allow diffusion. The tubes are surrounded with dialysis fluid, which is the same as blood plasma. The concentration of waste products in the blood is much higher in the blood than in the dialysis fluid. This creates a concentration gradient, diffusion occurs and waste products leave the blood to the dialysis fluid, which then exits the machine and gets disposed of. The dialysis fluid has to be renewed continuously to keep the concentration gradient of waste products higher in the blood, thus ensuring that all waste products leave the blood. The clean blood is then returned to the patient’s vein. 

 
Advantages
Disadvantages
Kidney transplant
- patients can lead a more normal life
- cheaper for the NHS overall
- must take immunosuppressant drugs
- shortage or organ donors
- kidney only lasts 8-9 years
- can be rejected
Kidney dialysis
- available to all
- no need for immunosuppressant drugs
- patients must limit their salt and protein intake
- expensive for the NHS
- regular treatment so patient is unable to carry a normal life.

PSB

#42 Plant nutrition (English)


Plant Nutrition

1. Photosynthesis
The fundamental process by which plants manufacture carbohydrates from raw materials using energy from light.
Carbon dioxide + Water  ------(light)------> Glucose + Oxygen
6CO2             +   6H2O  ------(light)------>  C6H12O6  +    6O2
 Photosynthesis occurs in the leaves of a plant.

How photosynthesis happens

         Carbon dioxide and water enter the cell
         The cell traps light energy using chloroplasts.
         The energy is used to split water (H2O) into hydrogen and oxygen
         The oxygen is excreted outside the leaf to the atmosphere as a waste product
         The hydrogen reacts with carbon dioxide forming glucose.

Carbon dioxide supply

Land plants get their carbon dioxide from the air. There is only about 0.04% of it in the air but since the plants continuously carry out photosynthesis, there is always a concentration gradient. The carbon dioxide diffuses into the plants through tiny holes in the leaf called stomata. Then these molecules move through the air spaces between the spongy cells, through the cell walls, cell membranes and cytoplasm of the spongy and palisade cells, and finally into their chloroplasts.

Water supply

The water is absorbed by the roots of the plants. Then it is transported upwards through a hollow tube called the xylem vessel, until it reaches the leaf where photosynthesis takes place. It enters the leaf through holes in the xylem. Excess water leaves the cell through the stomata; this is called “transpiration.”

Light supply

The leaves are always exposed to sunlight at daytime. The green pigment, chlorophyll, found in the chloroplasts of plant cells absorbs light energy from the sun. The light penetrates the transparent layers on the leaf until it reaches the mesophyll layer, where photosynthesis takes place. Palisade cells are nearer to the surface of the leaf than the spongy cells, so they receive more of the light and make more photosynthesis. Guard cells are also able to photosynthesize.

Uses of produced glucose

For respiration
Converted into starch and stored
Turned into sucrose and transported to other parts of the plants

LIMITING FACTORS

Something present in the environment in such short supply that it restricts life processes.
There are several factors affecting the rate of photosynthesis. The most important ones are:

-   Light intensity
-   Concentration of carbon dioxide
-   Temperature




Light intensity

In the first part of the curve, as light intensity increases, the rate of photosynthesis increases. It is then a limiting factor as the rate of the reaction is being kept low or limited by the lack of light.

However, it eventually reaches a point where the plant is photosynthesizing as fast as it can. Light stops being a limiting factor as even if more light is shone on the plant, the rate of the reaction is still the same. This is probably because another limiting factor is holding it back.

Carbon dioxide

CO2 is a key limiting factor. In perfect conditions, a lack of CO2 holds back the rate or reaction. Like light intensity, as a plant is given more carbon dioxide it will photosynthesize faster. This is so until it reaches its maximum. From here onwards, something else must be the limiting factor.

Temperature

The chemical reactions of photosynthesis can only take place very slowly at low temperature, so a plant can photosynthesize faster on a warm day than on a cold one. However, plants can’t photosynthesize either if it gets too hot.

Greenhouses

A green house is a placed covered by transparent polythene. In green houses, the limiting factors of photosynthesis are eliminated, and the plants are provided the most suitable conditions for a healthy, rapid growth.

The soil in green houses is fertilized and very rich in mineral ions, assuring healthy, large yields. More carbon dioxide is supplied to the crops for faster photosynthesis. The polythene walls and ceiling allow heat waves and light rays only to enter and prevent harmful waves, thus providing a high light intensity and optimum temperature, sometimes a heating system is used too. A watering system is also present. The disadvantages of green houses are that it is too small to give a large yield and that it is expensive.

2. Leaf structure

Upper Epidermis: it is a layer of cells that covers the leaf and protects it. It is covered by a layer of wax called cuticle.

Mesophyll Layer:

·         Palisade Mesophyll: a layer of palisade cells which carry out most of photosynthesis
·         Spongy Mesophyll: a layer of spongy cells beneath the palisade layer, they carry out photosynthesis and store nutrients.

Vascular Bundle: it is a group of phloem and xylem vessels that transport water and minerals to and from the leaves.

Lower Epidermis: similar to the upper epidermis, only that it contains a special type of cells called guard cells. Guard cells are a specialized type of cells that control the passage of carbon dioxide into the cell and the passage of oxygen out of the cell by opening and closing the stomata (a hole in the leaf through which gases pass) so guard cells are responsible for the gas exchange.

How guard cells work

At daytime, the guard cells open the stomata to allow gaseous exchange, this occurs according to the following steps:

         Sunlight increases the potassium concentration in the vacuoles of the guard cells, the water potential decreases making a gradient between the guard cells and the surrounding epidermal cells.
         Water moves by osmosis into the guard cells from the epidermal cells.
         The water raises the pressure inside the guard cells.
         The cell wall adjacent to the stomata is thicker and less stretchable then the cell wall on the other side.
         The pressure expands the whole cell except for the inner cell wall, creating a curve and a pore between the two guard cells.
         The stoma opens.

At night however, the mechanism is opposite:

         Potassium level decreases in the vacuole of the guard cells,
         Water potential increases in the cell and water diffuses out of it,
         The guard cells straighten up because of low pressure closing the stoma.

3. Mineral requirements

The plant is also in need for mineral ions to control chemical activities, grow, and produce materials. The most important minerals are:

Mg+2 (magnesium ions): they are important for the production of chlorophyll (chlorophyll synthesis). A lack of it results in lack of photosynthesis and wilting of the leaves.
Nitrates: these are the sources of nitrogen; they are required to make amino acids and proteins by combining with glucose. A lack of it results in deformation of the plant structure making it small and weak.

Fertilizers:

Sometimes the soil is lacking of the mineral ions needed. This problem can be solved by adding fertilizers to the soil. Fertilizers are chemical compounds rich in the mineral ions needed by the plants. They help the plants grow faster, increase in size and become greener. They simply make them healthier and increase the crop yield. But there are disadvantages of fertilizers, such as:

- Excess minerals and chemicals can enter a nearby river polluting it and creating a layer of green algae on the surface of it, causing lack of light in the river, thus preventing the aqua plants photosynthesizing.
- When living organisms in the river or lake die, decomposers such as bacteria multiply and decay, respire using oxygen. Eutrophication takes place eventually.

PSB